NEET 2025 Toughest Chapters in Physics, Biology and Chemistry

Physics, Biology, and Chemistry are the toughest chapters in the NEET 2025 Exam. Measuring the difficulty level is subjective, but you can find out which topics are challenging for everyone. Preparing for NEET 2025 may appear to be a difficult task, particularly when dealing with the most difficult chapters of NEET.
These difficult areas in Physics, Chemistry, and Biology demand a careful approach. Ray Optics and Semiconductors are two chapters in Physics that can be difficult to understand. Chemistry presents difficulties with coordination compounds and the d & f block. Read complete articles to know the toughest chapters in physics, biology, and chemistry.
NEET 2025 Toughest Chapters in Biology
The National Eligibility and Entrance Test (NEET) is one of the most difficult exams for aspiring doctors in India. Biology is an important subject in NEET, accounting for 50% of total marks. Some important chapters for NEET Biology may be tougher due to their complicated nature, depth, and degree of awareness required. Here are some of the toughest neet important chapters that students commonly find challenging:
1. Genetics and Evolution
This is a concept-heavy chapter that requires an in-depth knowledge of inheritance patterns, mutations, and molecular genetics. The complexity of concepts such as Mendelian genetics, genetic disorders, and evolutionary theories makes things difficult. Key topics include Mendelian inheritance, DNA structure, genetic disorders, evolutionary theories, and Hardy-Weinberg equilibrium.
2. Human Physiology
This chapter covers different detailed processes and systems, including the circulatory system, digestive system, excretory system, and neurological control. Understanding the functioning of different organs, hormones, enzymes, and processes can be challenging. Key topics include the circulatory system, nervous system, excretory system, digestive system, and endocrine system.
3. Reproduction
In-depth information about the male and female reproductive systems, gametogenesis, hormonal regulation, and sexual reproduction in plants are covered in this chapter, which covers both human and plant reproduction. Key topics include male and female reproductive systems, gametogenesis, the menstrual cycle, fertilization, and sexual reproduction in plants.
4. Cell Structure and Function
This chapter covers cellular organelles, their functions, and structures. It demands a thorough understanding of cell biology, biochemistry, and molecular biology.
Key topics include cell structure, cell membrane, transport processes, photosynthesis, and cellular respiration.
5. Plant Physiology
Transpiration, respiration, photosynthesis, and plant growth regulators are all complex processes that require a thorough understanding. Key topics include photosynthesis, transpiration, respiration, plant growth and development, and phytohormones.
6. Biomolecules
This chapter needs memorization of a huge amount of material about the structure and activities of diverse biomolecules such as proteins, lipids, nucleic acids, and carbohydrates. Proteins, carbohydrates, nucleic acids, enzymes, and lipids are some of the key topics.
7. Ecology and Environment
The chapter combines theoretical principles and data interpretation (graphics, statistics), which may be difficult for some students. It also discusses ecological dynamics, biodiversity, and environmental challenges. Key topics include ecosystems, biodiversity, conservation, pollution, and climate change.
8. Microbes in Human Welfare
Understanding the diverse positive and harmful functions that microbes play in the lives of humans, from industrial uses to diseases, requires the capacity to link biological concepts. Key topics include microorganisms in food production, illnesses, and their function in biotechnology.
Check Out: NEET Previous Year Papers
NEET 2025 Toughest Chapters in Physics
Physics in NEET is widely regarded as one of the most difficult areas of the examination due to its conceptual complexity and mathematical character. Some chapters require a more in-depth understanding of laws, principles, and applications, while others need excellent problem-solving abilities. Here are the most difficult chapters in NEET Physics that many students find difficult.
Electrodynamics
Because of the mathematical ideas involved, topics like electrostatics, electric fields, capacitance, and circuits can be complicated.
Modern physics
Ideas like nuclear physics, atomic structure, and quantum mechanics frequently ask for mathematical formulations and abstract thought.
Thermodynamics
Because of their conceptual depth and requirement for problem-solving, the laws of thermodynamics, heat engines, and entropy can be difficult to understand.
Mechanics
When dealing with several variables and forces, concepts like rotational motion, oscillations, and waves can be challenging.
Optics
A strong knowledge of ray diagrams and wave behavior is necessary for geometric and wave optics, which includes lenses, mirrors, interference, and diffraction.
Fluid mechanics
The complicated relationships between pressure, velocity, and height make concepts like buoyancy, Bernoulli's principle, and fluid dynamics difficult to understand.
Kinematics and Dynamics
Excellent analytical skills are often required to solve problems asking multiple motions and complex force relations.
Check Out: NEET Revision Books
NEET 2025 Toughest Chapters in Chemistry
Chemistry is a mysterious subject, yet many students find it easier than physics in terms of the NEET exam. Here are some of the most difficult chapters in the NEET Chemistry syllabus.
d & f Block
The d and f block elements are important since they support many other concepts, yet the chapter is the most difficult to master.
Coordination Compounds
You'll be studying metals and molecules moving around, and determining their steps can be challenging.
Equilibrium
Equilibrium is all about balance. Imagine a seesaw the goal is to keep things level. Chemistry is about balancing reactions. It may appear to be a juggling act at first, but with practice, it becomes less difficult.
GOC 1 & GOC 2
General Organic Chemistry (GOC) is a long chapter covering the fundamentals of organic chemistry. It may appear to be a lot, but doing it step by step makes it more enjoyable rather than tough.
P Block
P block elements are like a sea of information. You discover something fresh every time you go exploring.
Check Out: NEET Test series
How Can I Get Ready for NEET's Toughest Chapters?
To prepare for the most difficult chapters in NEET, focus on deeply understanding the main ideas, practice a large number of questions from various sources, use visual aids, seek expert guidance, regularly revise key points, and incorporate mock tests to simulate exam pressure, all while prioritizing the chapters with the highest weightage in the exam.
Identify High-Weightage Chapters
Analyse previous year's papers to find the chapters that appear frequently and carry more marks, then devote extra study time to these sections.
Master Basic Concepts
Before moving on to complicated applications, make sure you understand the fundamental ideas and theories in each chapter.
NCERT as Foundation
Use NCERT textbooks as your major source of information to ensure that you understand all of the concepts mentioned.
Practice Diverse Questions
To get a comprehensive understanding, answer questions from many sources such as previous year's papers, mock tests, and reference books.
Concept-Based Learning
Put a greater focus on comprehending the "why" behind the ideas than simply learning facts or formulas by heart.
Visual Aids and Diagrams
To help with memory retention and to visualize complicated procedures, use flowcharts, diagrams, and drawings.
Regular Revision
To avoid forgetting, review important formulas, ideas, and points regularly.
Time management
To become used to answering questions in the allocated amount of time, practice time management during practice exams.
Address Weak Areas
Identify your weak points in the hard chapters and devote extra time to practicing and improving them.
Read More: Study Material for NEET Exam 2025 in Hindi
NEET 2025 Toughest Chapters FAQs
Q1 - Which is the toughest chapter in NEET physical chemistry?
Ans - Thermodynamics and equilibrium are thought to be the most difficult topics in NEET chemistry. However, if you have practiced the concepts and numerical sections of both courses, you will be able to easily answer the correct questions.
Q2 - Is NEET Chemistry tough?
Ans - No, NEET chemistry isn't that difficult.
Q3 - Which is the hardest chapter in NEET Physics?
Ans - However, these are the most difficult chapters in the NEET Physics syllabus. Ray Optics is the study of how light travels and bends. Just when you think you've got it, a new type of question arises. Semiconductors - This chapter may appear dull at first, but it becomes interesting in an unusual way.
Q4 - Is Chemistry harder than Physics in NEET?
Ans - Students studying for JEE and NEET may be aware that Chemistry is a higher-scoring, easier-to-understand topic than Physics.
Q5 - Which year had the toughest NEET exam?
Ans - This section will provide an in-depth analysis of these specific years, stressing the elements that contributed to the problems presented by the examination papers. The Physics component of the 2016 NEET examination is widely regarded as the most difficult in its history.